NVP-BEZ235 Inhibits Renal Cell Carcinoma by Targeting TAK1 and PI3K/Akt/mTOR Pathways
In spite of the promising in vitro and preclinical results, dual PI3K/Akt/mTOR inhibitor NVP-BEZ235, and ATP-competitive mTOR inhibitor PP242 both failed to confirm their inhibitory efficacy against renal cell carcinoma (RCC) in clinical settings. Therefore, a better understanding of the molecular m...
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| Main Authors: | , , , , |
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| Format: | Book |
| Published: |
Frontiers Media S.A.,
2022-01-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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