CD46 splice variant enhances translation of specific mRNAs linked to an aggressive tumor cell phenotype in bladder cancer

• Main Authors: Jin Zeng (Author), Hua Xu (Author), Chunhua Huang (Author), Yi Sun (Author), Haibing Xiao (Author), Gan Yu (Author), Hui Zhou (Author), Yangjun Zhang (Author), Weimin Yao (Author), Wei Xiao (Author), Junhui Hu (Author), Lily Wu (Author), Jinchun Xing (Author), Tao Wang (Author), Zhiqiang Chen (Author), Zhangqun Ye (Author), Ke Chen (Author)
• Format: Book
• Published: Elsevier, 2021-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

CD46 is well known to be involved in diverse biological processes. Although several splice variants of CD46 have been identified, little is known about the contribution of alternative splicing to its tumorigenic functions. In this study, we found that exclusion of CD46 exon 13 is significantly incre...