Klotho induces insulin resistance possibly through interference with GLUT4 translocation and activation of Akt, GSK3β, and PFKfβ3 in 3T3-L1 adipocyte cells

• Những tác giả chính: Mohamad Hasannejad (Tác giả), Seyed Ziaaldin Samsamshariat (Tác giả), Armita Esmaili (Tác giả), Ali Jahanian-Najafabadi (Tác giả)
• Định dạng: Sách
• Được phát hành: Wolters Kluwer Medknow Publications, 2019-01-01T00:00:00Z.
• Những chủ đề: article
• Truy cập trực tuyến: Connect to this object online.

Klotho is considered as an anti-aging factor inducing insulin resistance and involved in type 2 diabetes. However, mechanisms by which klotho induces insulin resistance remain to be understood. Thus, in this study, we aimed to evaluate possible interference points of klotho with insulin signaling pa...