Klotho induces insulin resistance possibly through interference with GLUT4 translocation and activation of Akt, GSK3β, and PFKfβ3 in 3T3-L1 adipocyte cells

• Главные авторы: Mohamad Hasannejad (Автор), Seyed Ziaaldin Samsamshariat (Автор), Armita Esmaili (Автор), Ali Jahanian-Najafabadi (Автор)
• Формат: ‌
• Опубликовано: Wolters Kluwer Medknow Publications, 2019-01-01T00:00:00Z.
• Предметы: article
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Klotho is considered as an anti-aging factor inducing insulin resistance and involved in type 2 diabetes. However, mechanisms by which klotho induces insulin resistance remain to be understood. Thus, in this study, we aimed to evaluate possible interference points of klotho with insulin signaling pa...