Ruthenium red improves blastocyst developmental competence by regulating mitochondrial Ca2+ and mitochondrial functions in fertilized porcine oocytes in vitro

• Autori principali: Ho-Geun JEGAL (Autore), Hyo-Jin PARK (Autore), Jin-Woo KIM (Autore), Seul-Gi YANG (Autore), Min-Ji KIM (Autore), Deog-Bon KOO (Autore)
• Natura: Libro
• Pubblicazione: The Society for Reproduction and Development, 2020-04-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Ruthenium red (RR) inhibits calcium (Ca2+) entry from the cytoplasm to the mitochondria, and is involved in maintenance of Ca2+ homeostasis in mammalian cells. Ca2+ homeostasis is very important for further embryonic development of fertilized oocytes. However, the effect of RR on mitochondria-Ca2+ (...