Micellar Nanocarriers of Hydroxytyrosol Are Protective against Parkinson's Related Oxidative Stress in an In Vitro hCMEC/D3-SH-SY5Y Co-Culture System

• Main Authors: Leah Mursaleen (Author), Brendon Noble (Author), Satyanarayana Somavarapu (Author), Mohammed Gulrez Zariwala (Author)
• Format: Knjiga
• Izdano: MDPI AG, 2021-05-01T00:00:00Z.
• Teme: article
• Online dostop: Connect to this object online.

Hydroxytyrosol (HT) is a natural phenolic antioxidant which has neuroprotective effects in models of Parkinson's disease (PD). Due to issues such as rapid metabolism, HT is unlikely to reach the brain at therapeutic concentrations required for a clinical effect. We have previously developed mic...