A Physiologically Based Pharmacokinetic Model for Predicting Diazepam Pharmacokinetics after Intravenous, Oral, Intranasal, and Rectal Applications

• Main Authors: Sundus Khalid (Author), Muhammad Fawad Rasool (Author), Imran Imran (Author), Abdul Majeed (Author), Hamid Saeed (Author), Anees ur Rehman (Author), Waseem Ashraf (Author), Tanveer Ahmad (Author), Yousef A. Bin Jardan (Author), Faleh Alqahtani (Author)
• Format: Book
• Published: MDPI AG, 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Diazepam is one of the most prescribed anxiolytic and anticonvulsant that is administered through intravenous (IV), oral, intramuscular, intranasal, and rectal routes. To facilitate the clinical use of diazepam, there is a need to develop formulations that are convenient to administer in ambulatory...