Paricalcitol prevents MAPK pathway activation and inflammation in adriamycin-induced kidney injury in rats

• Main Authors: Amanda Lima Deluque (Author), Lucas Ferreira de Almeida (Author), Beatriz Magalhães Oliveira (Author), Cláudia Silva Souza (Author), Ana Lívia Dias Maciel (Author), Heloísa Della Coletta Francescato (Author), Cleonice Giovanini (Author), Roberto Silva Costa (Author), Terezila Machado Coimbra (Author)
• Format: Book
• Published: Korean Society of Pathologists & the Korean Society for Cytopathology, 2024-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background Activation of the mitogen-activated protein kinase (MAPK) pathway induces uncontrolled cell proliferation in response to inflammatory stimuli. Adriamycin (ADR)-induced nephropathy (ADRN) in rats triggers MAPK activation and pro-inflammatory mechanisms by increasing cytokine secretion, sim...