Over-expression of 60s ribosomal L23a is associated with cellular proliferation in SAG resistant clinical isolates of Leishmania donovani.

• Main Authors: Sanchita Das (Author), Priyanka Shah (Author), Rajendra K Baharia (Author), Rati Tandon (Author), Prashant Khare (Author), Shyam Sundar (Author), Amogh A Sahasrabuddhe (Author), M I Siddiqi (Author), Anuradha Dube (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<h4>Background</h4>Sodium antimony gluconate (SAG) unresponsiveness of Leishmania donovani (Ld) had effectively compromised the chemotherapeutic potential of SAG. 60s ribosomal L23a (60sRL23a), identified as one of the over-expressed protein in different resistant strains of L.donovani a...