Isoflurane-lipid emulsion injection as an anticonvulsant and neuroprotectant treatment for nerve agent exposure

• Prif Awduron: Jishnu K. S. Krishnan (Awdur), John R. Moffett (Awdur), Narayanan Puthillathu (Awdur), Erik A. Johnson (Awdur), Aryan M. Namboodiri (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: Frontiers Media S.A., 2024-10-01T00:00:00Z.
• Pynciau: article
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We have shown that briefly inhaled isoflurane rapidly halts convulsions and protects the central nervous system (CNS) from organophosphate-induced neuronal loss when administered at 5% for 5 min, even as late as 1 h after organophosphate exposure. In the current study we investigated if an injectabl...