A systematic strategy for identifying causal single nucleotide polymorphisms and their target genes on Juvenile arthritis risk haplotypes

• Main Authors: Kaiyu Jiang (Author), Tao Liu (Author), Susan Kales (Author), Ryan Tewhey (Author), Dongkyeong Kim (Author), Yungki Park (Author), James N. Jarvis (Author)
• Format: Book
• Published: BMC, 2024-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Although genome-wide association studies (GWAS) have identified multiple regions conferring genetic risk for juvenile idiopathic arthritis (JIA), we are still faced with the task of identifying the single nucleotide polymorphisms (SNPs) on the disease haplotypes that exert the bi...