Development of nintedanib nanosuspension for inhaled treatment of experimental silicosis

• Main Authors: Luisa Helena Andrade da Silva (Author), Juliana Borges Vieira (Author), Marianna Ribeiro Cabral (Author), Mariana Alves Antunes (Author), Daiheon Lee (Author), Fernanda Ferreira Cruz (Author), Justin Hanes (Author), Patricia Rieken Macedo Rocco (Author), Marcelo Marcos Morales (Author), Jung Soo Suk (Author)
• Format: Book
• Published: Wiley, 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Silicosis is an irreversible and progressive fibrotic lung disease caused by massive inhalation of crystalline silica dust at workplaces, affecting millions of industrial workers worldwide. A tyrosine kinase inhibitor, nintedanib (NTB), has emerged as a potential silicosis treatment due to...