Poor statistical power in population-based association study of gene interaction

• Prif Awduron: Jiarui Ma (Awdur), Jian Li (Awdur), Yuqi Chen (Awdur), Zhen Yang (Awdur), Yungang He (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: BMC, 2024-04-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

Abstract Background Statistical epistasis, or "gene-gene interaction" in genetic association studies, means the nonadditive effects between the polymorphic sites on two different genes affecting the same phenotype. In the genetic association analysis of complex traits, nevertheless, the re...