Leishmania aethiopica field isolates bearing an endosymbiontic dsRNA virus induce pro-inflammatory cytokine response.

• Main Authors: Haroun Zangger (Author), Asrat Hailu (Author), Chantal Desponds (Author), Lon-Fye Lye (Author), Natalia S Akopyants (Author), Deborah E Dobson (Author), Catherine Ronet (Author), Hashim Ghalib (Author), Stephen M Beverley (Author), Nicolas Fasel (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2014-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Infection with Leishmania parasites causes mainly cutaneous lesions at the site of the sand fly bite. Inflammatory metastatic forms have been reported with Leishmania species such as L. braziliensis, guyanensis and aethiopica. Little is known about the factors underlying such exacerbated clinical pr...