Pharmacological Modulation of BET Family in Sepsis

• Ngā kaituhi matua: Nian Wang (Author), Runliu Wu (Author), Paul B. Comish (Author), Rui Kang (Author), Daolin Tang (Author)
• Hōputu: Pukapuka
• I whakaputaina: Frontiers Media S.A., 2021-03-01T00:00:00Z.
• Ngā marau: article
• Urunga tuihono: Connect to this object online.

The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis 3.0) recommended defining sepsis as a life-threatening organ dysfunction caused by the host's uncontrolled response to infection. The bromodomain and extra-terminal (BET) protein family (such as BRD2, BRD3, and BR...