Quetiapine Albumin Nanoparticles as an Efficacious Platform for Brain Deposition and Potentially Improved Antipsychotic Activity

• Main Authors: Hend Mohamed Abdel-Bar (Author), Alaa S. Tulbah (Author), Hany W. Darwish (Author), Rania Salama (Author), Ibrahim A. Naguib (Author), Heba A. Yassin (Author), Hadel A. Abo El-Enin (Author)
• Format: Book
• Published: MDPI AG, 2023-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Quetiapine (QP) is a second-generation short-acting antipsychotic drug extensively metabolized in the liver, producing pharmacologically inactive metabolites and leading to diminished bioavailability. Therefore, this study aimed to develop an intravenous QP albumin nanoparticles (NPs) system for imp...