KINETIC MODELING ON AMIDE HYDROLYSIS, DRUG RELEASE AND MUCOSAL PERMEATION OF INDOMETHACIN IN THE COMPOSITION OF SELECTED SEMISOLID VEHICLES

KINETIC MODELING ON AMIDE HYDROLYSIS, DRUG RELEASE AND MUCOSAL PERMEATION OF INDOMETHACIN IN THE COMPOSITION OF SELECTED SEMISOLID VEHICLES

The present study aims to reveal the role of a semi-solid vehicle in the composition of Indomethacin dosage forms for their physical and chemical stability, in vitro and ex vivo behavior. Three types of hydrogels and emulgels were prepared with gelling agents Methylcellulose 2%, Poloxamer 407 20% an...

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Main Authors: Nadezhda A. Ivanova (Author), Tsvetelina S. Stefanova (Author), Ivelin R. Iliev (Author), Georgi S. Stoyanov (Author), Kameliya Zh. Bratoeva (Author)
Format: Book
Published: Peytchinski Publishing, 2018-12-01T00:00:00Z.
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