Altering the inhibitory kinetics and molecular conformation of maltase by Tangzhiqing (TZQ), a natural α-glucosidase inhibitor

• Main Authors: Yanfen Li (Author), Xiaomao Zhang (Author), Ruihua Wang (Author), Lu Han (Author), Wei Huang (Author), Hong Shi (Author), Baohe Wang (Author), Ziqiang Li (Author), Shaolan Zou (Author)
• Format: Book
• Published: BMC, 2020-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Tangzhiqing (TZQ), as a potential α-glycosidase inhibitor, possesses postprandial hypoglycaemic effects on maltose in humans. The aim of this study was to investigate the mechanisms by which TZQ attenuates postprandial glucose by interrupting the activity of maltase, including in...