Gut microbiota mediates the absorption of FLZ, a new drug for Parkinson's disease treatment
The gut microbiota plays an important role in regulating the pharmacokinetics and pharmacodynamics of many drugs. FLZ, a novel squamosamide derivative, has been shown to have neuroprotective effects on experimental Parkinson's disease (PD) models. FLZ is under phase Ⅰ clinical trial now, while...
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Elsevier,
2021-05-01T00:00:00Z.
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