Inhibition of Activin/Myostatin signalling induces skeletal muscle hypertrophy but impairs mouse testicular development

• मुख्य लेखकों: Danielle Vaughan (लेखक), Olli Ritvos (लेखक), Robert Mitchell (लेखक), Oliver Kretz (लेखक), Maciej Lalowski (लेखक), Helge Amthor (लेखक), David Chambers (लेखक), Antonios Matsakas (लेखक), Arja Pasternack (लेखक), Henry Collins-Hooper (लेखक), Randy Ballesteros (लेखक), Tobias B. Huber (लेखक), Bernd Denecke (लेखक), Darius Widera (लेखक), Abir Mukherjee (लेखक), Ketan Patel (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: PAGEPress Publications, 2020-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Numerous approaches are being developed to promote post-natal muscle growth based on attenuating Myostatin/Activin signalling for clinical uses such as the treatment neuromuscular diseases, cancer cachexia and sarcopenia. However there have been concerns about the effects of inhibiting Activin on ti...