DPHB, a diarylheptane from Alpinia officinarum Hance, ameliorates insulin resistance: A network pharmacology and in vitro study

• Main Authors: Xiangyi Li (Author), Huan Wen (Author), Yuxin Zhang (Author), Aixia Liu (Author), Xuguang Zhang (Author), Minghai Fu (Author), Yipeng Pan (Author), Jian Xu (Author), Junqing Zhang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

(4E)-7-(4-Hydroxy-3-methoxyphenyl)-1-phenylhept-4-en-3-one (DPHB) derived from A. officinarum Hance has been reported to exert anti-inflammatory and anti-insulin resistance (IR) effects. We explored the molecular mechanism of DPHB ameliorating IR through network pharmacological prediction and in vit...