Clinico-mutational profile and the impact of splenectomy in children with glucose-6-phosphate isomerase deficiency

• Main Authors: Abhilasha Sampagar (Author), Abhishek Chandira (Author), Swapnil Pattanshetti (Author), Santosh Kurbet (Author), Ashwini Doddannavar (Author), Krishna Prasanna (Author)
• Format: Book
• Published: Elsevier, 2024-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: There is a lack of literature on the role of splenectomy in hemolytic anemias due to glucose-6-phosphate isomerase (GPI) deficiency. GPI deficiency is a rare red blood cell (RBC) enzymopathy of the glycolytic pathway. Most present with severe disease requiring frequent transfusions. In t...