Vascular Remodelling and Mesenchymal Transition in Systemic Sclerosis

• প্রধান লেখক: Pier Andrea Nicolosi (লেখক), Enrico Tombetti (লেখক), Norma Maugeri (লেখক), Patrizia Rovere-Querini (লেখক), Silvia Brunelli (লেখক), Angelo A. Manfredi (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Hindawi Limited, 2016-01-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Fibrosis of the skin and of internal organs, autoimmunity, and vascular inflammation are hallmarks of Systemic Sclerosis (SSc). The injury and activation of endothelial cells, with hyperplasia of the intima and eventual obliteration of the vascular lumen, are early features of SSc. Reduced capillary...