Angiopoietin-like protein 4 is an exercise-induced hepatokine in humans, regulated by glucagon and cAMP

• Main Authors: Bodil Ingerslev (Author), Jakob S. Hansen (Author), Christoph Hoffmann (Author), Jens O. Clemmesen (Author), Niels H. Secher (Author), Mika Scheler (Author), Martin Hrabĕ de Angelis (Author), Hans U. Häring (Author), Bente K. Pedersen (Author), Cora Weigert (Author), Peter Plomgaard (Author)
• Format: Book
• Published: Elsevier, 2017-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Angiopoietin-like protein-4 (ANGPTL4) is a circulating protein that is highly expressed in liver and implicated in regulation of plasma triglyceride levels. Systemic ANGPTL4 increases during prolonged fasting and is suggested to be secreted from skeletal muscle following exercise. Methods...