Structure and Dynamics of a Site-Specific Labeled Fc Fragment with Altered Effector Functions

Antibody-drug conjugates (ADCs) are a class of biotherapeutic drugs designed as targeted therapies for the treatment of cancer. Among the challenges in generating an effective ADC is the choice of an effective conjugation site on the IgG. One common method to prepare site-specific ADCs is to enginee...

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Bibliographic Details
Main Authors: D. Travis Gallagher (Author), Chris McCullough (Author), Robert G. Brinson (Author), Joomi Ahn (Author), John P. Marino (Author), Nazzareno Dimasi (Author)
Format: Book
Published: MDPI AG, 2019-10-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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