Automated quantification of aligned collagen for human breast carcinoma prognosis

• Main Authors: Jeremy S Bredfeldt (Author), Yuming Liu (Author), Matthew W Conklin (Author), Patricia J Keely (Author), Thomas R Mackie (Author), Kevin W Eliceiri (Author)
• Format: Book
• Published: Elsevier, 2014-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Mortality in cancer patients is directly attributable to the ability of cancer cells to metastasize to distant sites from the primary tumor. This migration of tumor cells begins with a remodeling of the local tumor microenvironment, including changes to the extracellular matrix and the r...