Enzymatic Activity of CD73 Modulates Invasion of Gliomas via Epithelial-Mesenchymal Transition-Like Reprogramming

• Main Authors: Julia Tsiampali (Author), Silke Neumann (Author), Beatriz Giesen (Author), Katharina Koch (Author), Donata Maciaczyk (Author), Christoph Janiak (Author), Daniel Hänggi (Author), Jaroslaw Maciaczyk (Author)
• Format: Book
• Published: MDPI AG, 2020-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Glioblastoma (GBM) is the most aggressive malignant primary brain tumour in adulthood. Despite strong research efforts current treatment options have a limited impact on glioma stem-like cells (GSCs) which contribute to GBM formation, progression and chemoresistance. Invasive growth of GSCs is in pa...