Identification of Novel Fibrosis Modifiers by In Vivo siRNA Silencing

• Main Authors: Elisabeth H. Vollmann (Author), Lizhi Cao (Author), Aldo Amatucci (Author), Taylor Reynolds (Author), Stefan Hamann (Author), Isin Dalkilic-Liddle (Author), Thomas O. Cameron (Author), Markus Hossbach (Author), Kevin J. Kauffman (Author), Faryal F. Mir (Author), Daniel G. Anderson (Author), Tatiana Novobrantseva (Author), Victor Koteliansky (Author), Tatiana Kisseleva (Author), David Brenner (Author), Jeremy Duffield (Author), Linda C. Burkly (Author)
• Format: Book
• Published: Elsevier, 2017-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Fibrotic diseases contribute to 45% of deaths in the industrialized world, and therefore a better understanding of the pathophysiological mechanisms underlying tissue fibrosis is sorely needed. We aimed to identify novel modifiers of tissue fibrosis expressed by myofibroblasts and their progenitors...