Effectiveness and safety of available preventive tuberculosis treatment regimens for children and adolescents: protocol for a systematic review and network meta-analysis

• Main Authors: Ivan D Florez (Author), Vanessa Sabella-Jiménez (Author), Yenifer Hoyos Mendez (Author), Dione Benjumea-Bedoya (Author), Andrés Felipe Estupiñán-Bohorquez (Author), Jorge Acosta-Reyes (Author)
• Format: Book
• Published: BMJ Publishing Group, 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction Approximately 5%-10% of individuals with untreated latent tuberculosis infection (LTBI) will progress to active tuberculosis (TB). Children are at a higher risk for progression to TB disease than adults. Isoniazid prophylaxis treatment period is long and can cause liver damage. Alternat...