Effect of antibody-mediated connective tissue growth factor neutralization on lung edema in ventilator-induced lung injury in rats

• Asıl Yazarlar: Charissa E. van den Brom (Yazar), Caitlin Bozic (Yazar), Chantal A. Polet (Yazar), Annabel Bongers (Yazar), Anita M. Tuip-de Boer (Yazar), Roselique Ibelings (Yazar), Joris J. T. H. Roelofs (Yazar), Nicole P. Juffermans (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: BMC, 2024-05-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Abstract Background Acute respiratory distress syndrome (ARDS) is characterized by alveolar edema that can progress to septal fibrosis. Mechanical ventilation can augment lung injury, termed ventilator-induced lung injury (VILI). Connective tissue growth factor (CTGF), a mediator of fibrosis, is inc...