Integrative genomic analyses of APOBEC-mutational signature, expression and germline deletion of APOBEC3 genes, and immunogenicity in multiple cancer types
Abstract Background Although APOBEC-mutational signature is found in tumor tissues of multiple cancers, how a common germline APOBEC3A/B deletion affects the mutational signature remains unclear. Methods Using data from 10 cancer types generated as part of TCGA, we performed integrative genomic and...
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| Main Authors: | , , , , , , , , |
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| Format: | Book |
| Published: |
BMC,
2019-09-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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