Fast In Vitro Release and In Vivo Absorption of an Anti-Schizophrenic Drug Paliperidone from Its Soluplus^®/TPGS Mixed Micelles

• Main Authors: Ye Zhou (Author), Chenhui Wang (Author), Wenqian Liu (Author), Meiqing Yang (Author), Bohui Xu (Author), Yong Chen (Author)
• Format: Book
• Published: MDPI AG, 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The purpose of this study was to develop a drug delivery system for paliperidone (PPD) in order to provide a more effective therapeutic strategy for patients with acute schizophrenia. PPD-loaded Soluplus^®/TPGS mixed micelles (PPD-S/T-MM) were prepared using the thin-film hydra...