Propofol Induces Cardioprotection Against Ischemia-Reperfusion Injury via Suppression of Transient Receptor Potential Vanilloid 4 Channel

Propofol Induces Cardioprotection Against Ischemia-Reperfusion Injury via Suppression of Transient Receptor Potential Vanilloid 4 Channel

Ca2+ entry via the transient receptor potential vanilloid 4 (TRPV4) channel contributes to Ca2+ overload and triggers many pathophysiological conditions, including myocardial ischemia/reperfusion (I/R) injury. Propofol, a widely used intravenous anesthetic, attenuates myocardial I/R injury. However,...

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Main Authors: Binbin Wang (Author), Qiongfeng Wu (Author), Jie Liao (Author), Shaoshao Zhang (Author), Huixia Liu (Author), Cui Yang (Author), Qian Dong (Author), Ning Zhao (Author), Zhengrong Huang (Author), Kefang Guo (Author), Yimei Du (Author)
Format: Book
Published: Frontiers Media S.A., 2019-10-01T00:00:00Z.
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