Propofol Induces Cardioprotection Against Ischemia-Reperfusion Injury via Suppression of Transient Receptor Potential Vanilloid 4 Channel

• প্রধান লেখক: Binbin Wang (Author), Qiongfeng Wu (Author), Jie Liao (Author), Shaoshao Zhang (Author), Huixia Liu (Author), Cui Yang (Author), Qian Dong (Author), Ning Zhao (Author), Zhengrong Huang (Author), Kefang Guo (Author), Yimei Du (Author)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Frontiers Media S.A., 2019-10-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Ca2+ entry via the transient receptor potential vanilloid 4 (TRPV4) channel contributes to Ca2+ overload and triggers many pathophysiological conditions, including myocardial ischemia/reperfusion (I/R) injury. Propofol, a widely used intravenous anesthetic, attenuates myocardial I/R injury. However,...