Anti-Hyperuricemic and Nephroprotective Effects of Dihydroberberine in Potassium Oxonate- and Hypoxanthine-Induced Hyperuricemic Mice

• Main Authors: Lieqiang Xu (Author), Guoshu Lin (Author), Qiuxia Yu (Author), Qiaoping Li (Author), Liting Mai (Author), Juanjuan Cheng (Author), Jianhui Xie (Author), Yuhong Liu (Author), Ziren Su (Author), Yucui Li (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Phellodendri Chinese Cortex has long been used to treat hyperuricemia and gout. Berberine (BBR), its characteristic ingredient, has also been shown to be effective in alleviating monosodium urate crystals-triggered gout inflammation in vitro and in vivo. Dihydroberberine (DHB) is a hydrogenated deri...