Intranasal Delivery of Targeted Nanoparticles Loaded With miR-132 to Brain for the Treatment of Neurodegenerative Diseases

• Main Authors: Yu Su (Author), Bixi Sun (Author), Xiaoshu Gao (Author), Xinyue Dong (Author), Lanbo Fu (Author), Yingxin Zhang (Author), Zhulin Li (Author), Yue Wang (Author), Hongyu Jiang (Author), Bing Han (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Effective treatments for neurodegenerative diseases need to be developed. MiR132 is abundantly expressed in the brain, and it modulates neuron morphology and plays a key role in maintaining neuron survival. Regulating miR132 can effectively improve the symptoms of Alzheimer's disease. It can al...