CCL2 and Lactate from Chemotherapeutics-Treated Fibroblasts Drive Malignant Traits by Metabolic Rewiring in Low-Migrating Breast Cancer Cell Lines

CCL2 and Lactate from Chemotherapeutics-Treated Fibroblasts Drive Malignant Traits by Metabolic Rewiring in Low-Migrating Breast Cancer Cell Lines

While cytostatic chemotherapy targeting DNA is known to induce genotoxicity, leading to cell cycle arrest and cytokine secretion, the impact of these drugs on fibroblast-epithelial cancer cell communication and metabolism remains understudied. Our research focused on human breast fibroblast RMF-621...

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Main Authors: Maria Jesus Vera (Author), Iván Ponce (Author), Cristopher Almarza (Author), Gonzalo Ramirez (Author), Francisco Guajardo (Author), Karen Dubois-Camacho (Author), Nicolás Tobar (Author), Félix A. Urra (Author), Jorge Martinez (Author)
Format: Book
Published: MDPI AG, 2024-07-01T00:00:00Z.
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3rd Floor Main Library

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