In silico evaluation of rare codons and their positions in the structure of cytosine deaminase and substrate docking studies
Cytosine deaminase (CDase) is used with 5-fluorocytosine (5FC) for genetic cancer treatment. This approach has several undesirable features, such as a relatively poor turnover of 5FC and low prodrug conversion activities, thus limiting the overall therapeutic response. We previously reported the mol...
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Shiraz University of Medical Sciences,
2016-06-01T00:00:00Z.
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