In silico evaluation of rare codons and their positions in the structure of cytosine deaminase and substrate docking studies

Cytosine deaminase (CDase) is used with 5-fluorocytosine (5FC) for genetic cancer treatment. This approach has several undesirable features, such as a relatively poor turnover of 5FC and low prodrug conversion activities, thus limiting the overall therapeutic response. We previously reported the mol...

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Asıl Yazarlar: Mojtaba Mortazavi (Yazar), Navid Nezafat (Yazar), Manica Negahdaripour (Yazar), Ahmad Gholami (Yazar), Masoud Torkzadeh-Mahani (Yazar), Safa Lotfi (Yazar), Younes Ghasemi (Yazar)
Materyal Türü: Kitap
Baskı/Yayın Bilgisi: Shiraz University of Medical Sciences, 2016-06-01T00:00:00Z.
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