Instability of Acylcarnitines in Stored Dried Blood Spots: The Impact on Retrospective Analysis of Biomarkers for Inborn Errors of Metabolism

• Main Authors: Willemijn J. van Rijt (Author), Peter C. J. I. Schielen (Author), Yasemin Özer (Author), Klaas Bijsterveld (Author), Fjodor H. van der Sluijs (Author), Terry G. J. Derks (Author), M. Rebecca Heiner-Fokkema (Author)
• Format: Knjiga
• Izdano: MDPI AG, 2020-11-01T00:00:00Z.
• Teme: article
• Online dostop: Connect to this object online.

Stored dried blood spots (DBS) can provide valuable samples for the retrospective diagnosis of inborn errors of metabolism, and for validation studies for newborn blood spot screening programs. Acylcarnitine species are subject to degradation upon long-term storage at room temperature, but limited d...