The Effects of a Transgelin-2 Agonist Administered at Different Times in a Mouse Model of Airway Hyperresponsiveness

• Main Authors: Hong-Kai Yuan (Author), Jin Lu (Author), Xue-Ling Wang (Author), Zhi-Ying Lv (Author), Bo Li (Author), Weiliang Zhu (Author), Yong-Qing Yang (Author), Lei-Miao Yin (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Airway hyperresponsiveness (AHR) is one of the most important features of asthma. Our previous study showed that inhaled transgelin-2 agonist, TSG12, effectively reduced pulmonary resistance in a mouse model of asthma in a dose-dependent manner. However, the optimal administration time of TSG12 to r...