Gold nanoparticle-directed autophagy intervention for antitumor immunotherapy via inhibiting tumor-associated macrophage M2 polarization

• Main Authors: Siyue Zhang (Author), Fangyuan Xie (Author), Kaichun Li (Author), He Zhang (Author), You Yin (Author), Yuan Yu (Author), Guangzhao Lu (Author), Shihao Zhang (Author), Yan Wei (Author), Ke Xu (Author), Yan Wu (Author), Hong Jin (Author), Lan Xiao (Author), Leilei Bao (Author), Can Xu (Author), Yulin Li (Author), Ying Lu (Author), Jie Gao (Author)
• Format: Book
• Published: Elsevier, 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Tumor-associated macrophages (TAMs), one of the dominating constituents of tumor microenvironment, are important contributors to cancer progression and treatment resistance. Therefore, regulation of TAMs polarization from M2 phenotype towards M1 phenotype has emerged as a new strategy for tumor immu...