Salidroside Ameliorated Intermittent Hypoxia-Aggravated Endothelial Barrier Disruption and Atherosclerosis via the cAMP/PKA/RhoA Signaling Pathway

• Main Authors: Linyi Li (Author), Yunyun Yang (Author), Huina Zhang (Author), Yunhui Du (Author), Xiaolu Jiao (Author), Huahui Yu (Author), Yu Wang (Author), Qianwen Lv (Author), Fan Li (Author), Qiuju Sun (Author), Yanwen Qin (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Endothelial barrier dysfunction plays a key role in atherosclerosis progression. The primary pathology of obstructive sleep apnea-hypopnea syndrome is chronic intermittent hypoxia (IH), which induces reactive oxygen species (ROS) overproduction, endothelial barrier injury, and atheroscle...