Model-Informed Drug Development of New Cefoperazone Sodium and Sulbactam Sodium Combination (3:1): Pharmacokinetic/Pharmacodynamic Analysis and Antibacterial Efficacy Against Enterobacteriaceae

Model-Informed Drug Development of New Cefoperazone Sodium and Sulbactam Sodium Combination (3:1): Pharmacokinetic/Pharmacodynamic Analysis and Antibacterial Efficacy Against Enterobacteriaceae

Objective: Cefoperazone/sulbactam is a commonly used antibiotic combination against the extended-spectrum beta-lactamases (ESBLs)-producing bacteria. The objective of this study was to evaluate the efficacy of a new cefoperazone/sulbactam combination (3:1) for Enterobacteriaceae infection via model-...

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Main Authors: Xi-Wei Ji (Author), Xiao Zhu (Author), Yun Li (Author), Feng Xue (Author), Isabelle Hui San Kuan (Author), Qing-Feng He (Author), Xiang-Rui Meng (Author), Xiao-Qiang Xiang (Author), Yi-Min Cui (Author), Bo Zheng (Author)
Format: Book
Published: Frontiers Media S.A., 2022-07-01T00:00:00Z.
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