Model-Informed Drug Development of New Cefoperazone Sodium and Sulbactam Sodium Combination (3:1): Pharmacokinetic/Pharmacodynamic Analysis and Antibacterial Efficacy Against Enterobacteriaceae

• Asıl Yazarlar: Xi-Wei Ji (Yazar), Xiao Zhu (Yazar), Yun Li (Yazar), Feng Xue (Yazar), Isabelle Hui San Kuan (Yazar), Qing-Feng He (Yazar), Xiang-Rui Meng (Yazar), Xiao-Qiang Xiang (Yazar), Yi-Min Cui (Yazar), Bo Zheng (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Frontiers Media S.A., 2022-07-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Objective: Cefoperazone/sulbactam is a commonly used antibiotic combination against the extended-spectrum beta-lactamases (ESBLs)-producing bacteria. The objective of this study was to evaluate the efficacy of a new cefoperazone/sulbactam combination (3:1) for Enterobacteriaceae infection via model-...