Cysteines and Disulfide-Bridged Macrocyclic Mimics of Teixobactin Analogues and Their Antibacterial Activity Evaluation against Methicillin-Resistant Staphylococcus Aureus (MRSA)

Cysteines and Disulfide-Bridged Macrocyclic Mimics of Teixobactin Analogues and Their Antibacterial Activity Evaluation against Methicillin-Resistant Staphylococcus Aureus (MRSA)

Teixobactin is a highly potent cyclic depsipeptide which kills a broad range of multi-drug resistant, Gram-positive bacteria, such as Methicillin-resistant Staphylococcus aureus (MRSA) without detectable resistance. In this work, we describe the design and rapid synthesis of novel teixobactin analog...

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Main Authors: Ruba Malkawi (Author), Abhishek Iyer (Author), Anish Parmar (Author), Daniel G. Lloyd (Author), Eunice Tze Leng Goh (Author), Edward J. Taylor (Author), Sarir Sarmad (Author), Annemieke Madder (Author), Rajamani Lakshminarayanan (Author), Ishwar Singh (Author)
Format: Book
Published: MDPI AG, 2018-10-01T00:00:00Z.
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