Comparative Assessment of Docking Programs for Docking and Virtual Screening of Ribosomal Oxazolidinone Antibacterial Agents

• المؤلفون الرئيسيون: McKenna E. Buckley (مؤلف), Audrey R. N. Ndukwe (مؤلف), Pramod C. Nair (مؤلف), Santu Rana (مؤلف), Kathryn E. Fairfull-Smith (مؤلف), Neha S. Gandhi (مؤلف)
• التنسيق: كتاب
• منشور في: MDPI AG, 2023-02-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Oxazolidinones are a broad-spectrum class of synthetic antibiotics that bind to the 50S ribosomal subunit of Gram-positive and Gram-negative bacteria. Many crystal structures of the ribosomes with oxazolidinone ligands have been reported in the literature, facilitating structure-based design using m...