Disitamab vedotin: a novel antibody-drug conjugates for cancer therapy

• Main Authors: Fan Shi (Author), Yanli Liu (Author), Xuexiao Zhou (Author), Pei Shen (Author), Ran Xue (Author), Min Zhang (Author)
• Format: Book
• Published: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Human epidermal growth factor receptor 2 (HER2) regulates cell mitosis, proliferation, and apoptosis. Trastuzumab is a HER2-targeted monoclonal antibody (mAB), which can prolong the overall survival rate of patients with HER2 overexpression in later periods of gastric cancer and breast cancer. Altho...