Three-dimensional cell culture using CD9-positive cells isolated from marginal cell layer of intermediate lobe of rats sustains in vivo-like primary niche environment

• Main Authors: Kotaro HORIGUCHI (Author), Takehiro TSUKADA (Author), Saishu YOSHIDA (Author), Ken FUJIWARA (Author), Takashi NAKAKURA (Author), Morio AZUMA (Author), Ayano SHINDO (Author), Rumi HASEGAWA (Author), Shu TAKIGAMI (Author)
• Format: Book
• Published: The Society for Reproduction and Development, 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The adenohypophysis is composed of the anterior and intermediate lobes (AL and IL, respectively), and secretes hormones that play an important role in reproduction. CD9- and SOX2-double (CD9/SOX2) positive cells located in the marginal cell layer (MCL) facing the Rathke's cleft in the AL and IL...