The Catalytic Cycle of the Antioxidant and Cancer-Associated Human NQO1 Enzyme: Hydride Transfer, Conformational Dynamics and Functional Cooperativity

Human NQO1 [NAD(H):quinone oxidoreductase 1] is a multi-functional and stress-inducible dimeric protein involved in the antioxidant defense, the activation of cancer prodrugs and the stabilization of oncosuppressors. Despite its roles in human diseases, such as cancer and neurological disorders, a d...

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Main Authors: Ernesto Anoz-Carbonell (Author), David J. Timson (Author), Angel L. Pey (Author), Milagros Medina (Author)
Format: Book
Published: MDPI AG, 2020-08-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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