Insights Into Patient Variability During Ivacaftor-Lumacaftor Therapy in Cystic Fibrosis

• Main Authors: Patrick O. Hanafin (Author), Isabelle Sermet-Gaudelus (Author), Matthias Griese (Author), Matthias Kappler (Author), Helmut Ellemunter (Author), Carsten Schwarz (Author), John Wilson (Author), Marsha Tan (Author), Tony Velkov (Author), Gauri G. Rao (Author), Elena K. Schneider-Futschik (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: The advent of cystic fibrosis transmembrane conductance regulator protein (CFTR) modulators like ivacaftor have revolutionised the treatment of cystic fibrosis (CF). However, due to the plethora of variances in disease manifestations in CF, there are inherent challenges in unified respon...