Improving Breviscapine Oral Bioavailability by Preparing Nanosuspensions, Liposomes and Phospholipid Complexes

• Main Authors: Zilin Song (Author), Jiaojiao Yin (Author), Peifu Xiao (Author), Jin Chen (Author), Jingxin Gou (Author), Yanjiao Wang (Author), Yu Zhang (Author), Tian Yin (Author), Xing Tang (Author), Haibing He (Author)
• Format: Book
• Published: MDPI AG, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Breviscapine (BVP), a flavonoid compound, is widely used in the treatment of cardiovascular and cerebrovascular diseases; however, the low oral bioavailability and short half-life properties limit its application. The aim of this study was to investigate the three preparations for improving its oral...