Use of an In Vitro Skin Parallel Artificial Membrane Assay (Skin-PAMPA) as a Screening Tool to Compare Transdermal Permeability of Model Compound 4-Phenylethyl-Resorcinol Dissolved in Different Solvents

• Main Authors: Bálint Sinkó (Author), Vivien Bárdos (Author), Dániel Vesztergombi (Author), Szabina Kádár (Author), Petra Malcsiner (Author), Anne Moustie (Author), Chantal Jouy (Author), Krisztina Takács-Novák (Author), Sebastien Grégoire (Author)
• Format: Book
• Published: MDPI AG, 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Absorption through the skin of topically applied chemicals is relevant for both formulation development and safety assessment, especially in the early stages of development. However, the supply of human skin is limited, and the traditional in vitro methods are of low throughput. As an alternative, a...