In Vitro Synergistic Inhibition of HT-29 Proliferation and 2H-11 and HUVEC Tubulogenesis by Bacopaside I and II Is Associated with Ca²⁺ Flux and Loss of Plasma Membrane Integrity

• Main Authors: Yoko Tomita (Author), Eric Smith (Author), Helen M. Palethorpe (Author), Maryam Nakhjavani (Author), Kenny K. L. Yeo (Author), Amanda R. Townsend (Author), Timothy J. Price (Author), Andrea J. Yool (Author), Jennifer E. Hardingham (Author)
• Format: Book
• Published: MDPI AG, 2021-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We previously showed how triterpene saponin bacopaside (bac) II, purified from the medicinal herb <i>Bacopa monnieri</i>, induced cell death in colorectal cancer cell lines and reduced endothelial cell migration and tube formation, and further demonstrated a synergistic effect of a combi...